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Home > GENOMICS > EPIGENETIC PRODUCTS > Histone methylation > Histone methylation quantification > EpiQuik Global Pan-Methyl H4K20 Quant. Kit (Fluorometric)
EpiQuik Global Pan-Methyl H4K20 Quant. Kit (Fluorometric)
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Code | P-3071-96 |
---|---|
Description | EpiQuik Global Pan-Methyl H4K20 Quant. Kit (Fluorometric) |
Size | 96 samples |
Format | N/A |
Storage | see data sheet |
Data sheet | VIEW |
Addiotional product informations | VIEW |
Research area | Epigenetics |
Notes | The EpiQuik Global Pan-Methyl Histone H4-K20 Quantification Kit (Fluorometric) is a complete set of essential components, which enables the experimenter to measure global mono-, di- and tri-methylation of histone H4-K20. H4-K20 mono-methylation is involved in the maintenance of proper higher order structure of DNA and is consequently essential for chromosome condensation, as well as functioning in gene silencing. H4-K20 di-methylation has been described as a repressive chromatin domain and is involved in DNA damage response. H4-K20 tri-methylation acts as a passive feature or structure determinant for chromatin degradation and release and is an epigenetic marker of early apoptosis. The global H4-K20 methylation can be changed by inhibiton or activation of HMTs, thus quantitative detection of global methyl histone H4-K20 would provide useful information for better understanding epigenetic regulation of gene activation/repression as well as for developing HMT-targeted drugs |
Source | Epigentek |
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© 1995-2024 temaricerca.com - Tutti i diritti riservati - P.IVA 00674091202
Via XXI Ottobre 1944, 11/2, 40055 Castenaso (BO) - tel: 051 62 40 700 - fax: 051 62 40 706