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Home > PROTEOMICS > ELISA/CLIA/COLORIMETRIC KITS > R a t F r a c t a l k i n e / C X 3 C L 1 P i c o K i n e "! E L I S A K i t
R a t F r a c t a l k i n e / C X 3 C L 1 P i c o K i n e "! E L I S A K i t
AGGIUNGI AL CARRELLO
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Code | EK0358 |
---|---|
Description | R a t F r a c t a l k i n e / C X 3 C L 1 P i c o K i n e "! E L I S A K i t |
Size | 1 x 96T |
General information | Chemokine(C-X3-C motif) ligand 1(CX3CL1) is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine(in humans) and neurotactin(in mice). CX3CL1 is produced as a long protein(with 373-amino acid in humans) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk permits it to bind to the surface of certain cells. However a soluble(90 kD) version of this chemokine has also been observed. Soluble CX3CL1 potently chemoattracts T cells and monocytes, while the cell-bound chemokine promotes strong adhesion of leukocytes to activated endothelial cells, where it is primarily expressed. CX3CL1 elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1. Its gene is located on human chromosome 16 along with some CC chemokines known as CCL17 and CCL22. It can act as a mediator of smooth muscle cell migration in human atherosclerosis, rather than mediate inflammatory cell recruitment. |
ALTERNATIVE NAME | Fractalkine;C-X3-C motif chemokine 1;CX3C membrane-anchored chemokine;Neurotactin;Small-inducible cytokine D1;Processed fractalkine;Cx3cl1;Acc1, Fkn, Scyd1; |
Assay type | complete kit |
Detection method | ELISA |
Sample type | cell culture supernates, serum and plasma(heparin, EDTA). |
Range detection | 312pg/ml-20,000pg/ml |
Sensitivity | <10pg/ml |
Target species | Rat |
Protein id | O55145 |
Storage | S t o r e a t 4 ÚC f o r 6 m o n t h s , a t - 2 0 ÚC f o r 1 2 m o n t h s . A v o i d m u l t i p l e f r e e z e - t h a w c y c l e s ( S h i p p e d w i t h w e t i c e . ) |
Data sheet | www.bosterbio.com/datasheet.php?sku=EK0358 |
Source | Boster Immunoleader |
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© 1995-2024 temaricerca.com - Tutti i diritti riservati - P.IVA 00674091202
Via XXI Ottobre 1944, 11/2, 40055 Castenaso (BO) - tel: 051 62 40 700 - fax: 051 62 40 706