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Home > PROTEOMICS > ELISA/CLIA/COLORIMETRIC KITS > R a t D L L 4 P i c o K i n e "! E L I S A K i t
R a t D L L 4 P i c o K i n e "! E L I S A K i t
AGGIUNGI AL CARRELLO
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Code | EK1570 |
---|---|
Description | R a t D L L 4 P i c o K i n e "! E L I S A K i t |
Size | 1 x 96T |
General information | Delta like ligand 4 is a protein that in humans is encoded by the DLL4 gene. It is mapped to 15q15.1. This gene is a homolog of the Drosophila delta gene. DLL4 is a transmembrane ligand for Notch receptors that shows restricted expression to endothelial cells (ECs), in particular to arteries and capillaries, and is involved in vascular development, and it also appeared to be a major trigger of Notch receptor activities previously implicated in arterial and vascular development. DLL4 acts as a negative regulator of tumor angiogenesis, its blockade results in the striking uncoupling of tumor growth from vessel density, presenting a novel therapeutic approach even for tumors resistant to anti-VEGF therapies. In addition to it, this gene also plays an important role in promoting Th17 effector activity during mycobacterial challenge. |
ALTERNATIVE NAME | Delta-like protein 4 ;Drosophila Delta homolog 4 ;Delta4 ;Dll4 ; |
Assay type | complete kit |
Detection method | ELISA |
Sample type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
Range detection | 15.6pg/ml-1000pg/ml |
Sensitivity | <10pg/ml |
Target species | Rat |
Protein id | D3ZHH1 |
Storage | S t o r e a t 4 ÚC f o r 6 m o n t h s , a t - 2 0 ÚC f o r 1 2 m o n t h s . A v o i d m u l t i p l e f r e e z e - t h a w c y c l e s ( S h i p p e d w i t h w e t i c e . ) |
Data sheet | www.bosterbio.com/datasheet.php?sku=EK1570 |
Source | Boster Immunoleader |
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© 1995-2024 temaricerca.com - Tutti i diritti riservati - P.IVA 00674091202
Via XXI Ottobre 1944, 11/2, 40055 Castenaso (BO) - tel: 051 62 40 700 - fax: 051 62 40 706