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Home > GENOMICS > EPIGENETIC PRODUCTS > Modulators & Inhibitors > APHA Compound 8
APHA Compound 8
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Code | M45003-1 |
---|---|
Description | APHA Compound 8 |
Size | 1 mg |
Format | N/A |
Application | HDAC inhibitor |
Target species | N/A |
Host | N/A |
Storage | see data sheet |
Data sheet | VIEW |
Research area | Epigenetics |
Notes | APHA Compound 8 is a potent novel hydroxamate HDAC inhibitor, is in the same structural class as SAHA, an investigational drug standard currently in clinical trial. The IC50 for mouse HDAC1 is 0.5 µM. In a separate study, significant inhibition was found in the proliferation of MEL cells at 24 µM and differentiation, assayed as the accumulation of hemoglobin, at 5 µM |
Source | Epigentek |
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© 1995-2024 temaricerca.com - Tutti i diritti riservati - P.IVA 00674091202
Via XXI Ottobre 1944, 11/2, 40055 Castenaso (BO) - tel: 051 62 40 700 - fax: 051 62 40 706