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Home > GENOMICS > EPIGENETIC PRODUCTS > Modulators & Inhibitors > DR2313
DR2313
AGGIUNGI AL CARRELLO
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Code | M75002-1 |
---|---|
Description | DR2313 |
Size | 10 mg |
Format | N/A |
Application | PARP inhibitor |
Target species | N/A |
Host | N/A |
Storage | see data sheet |
Data sheet | VIEW |
Research area | Epigenetics |
Notes | PARP Inhibitor XI, DR2313 is a water soluble and brain-permeable pyrimidinone compound that functions as a Poly(ADP-ribose) polymerase inhibitor. Poly(ADP-ribose) polymerases, known as PARP, function by triggering DNA repair mechanisms and activating apoptosis in damaged cells. Studies show that DR2313 is a NAD+ utilizing enzyme which competitively inhibits Poly(ADP-ribose) polymerases but does not display selectivity among PARP-1 and PARP-2. In addition, in vitro studies of cerebral ischemia exhibiting an overactivation of PARP can be reduced by introducing DR2313 |
Source | Epigentek |
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© 1995-2024 temaricerca.com - Tutti i diritti riservati - P.IVA 00674091202
Via XXI Ottobre 1944, 11/2, 40055 Castenaso (BO) - tel: 051 62 40 700 - fax: 051 62 40 706