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Home > GENOMICS > EPIGENETIC PRODUCTS > Modulators & Inhibitors > MLN8237 (Alisertib)
MLN8237 (Alisertib)
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Code | M76000-1 |
---|---|
Description | MLN8237 (Alisertib) |
Size | 5 mg |
Format | N/A |
Application | Kinase inhibitor |
Target species | N/A |
Host | N/A |
Storage | see data sheet |
Data sheet | VIEW |
Research area | Epigenetics |
Notes | MLN8237 is a selective Aurora kinase A inhibitor with median IC50 of 61 nM. MLN8237 (Alisertib) is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the Aurora A kinase (serine/threonine protein kinase) with potential antineoplastic activity. MLN8237 (Alisertib) binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation |
Source | Epigentek |
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© 1995-2024 temaricerca.com - Tutti i diritti riservati - P.IVA 00674091202
Via XXI Ottobre 1944, 11/2, 40055 Castenaso (BO) - tel: 051 62 40 700 - fax: 051 62 40 706