Menu
CERCA ANTICORPI E PROTEINE
CERCA KIT-ELISA
prodotti
tema ricerca
Home > CELL BIOLOGY > CELL CULTURE MATRICES > Organoid and 3D Culture > Cultrex® HA-R-Spondin1-Fc 293T Cells
Cultrex® HA-R-Spondin1-Fc 293T Cells
AGGIUNGI AL CARRELLO
Oppure contattaci per avere ulteriori informazioni
info@temaricerca.com+39 051 62 40 700
Code | 3710-001-01 |
---|---|
Description | Cultrex® HA-R-Spondin1-Fc 293T Cells |
Size | 1 x 1 0 Ä6 c e l l s |
Storage | Liquid N2 |
Data sheet | VIEW |
Notes | Roof plate-specific Spondin-1 (R-Spondin 1 or RSPO1), also known as CRISTIN3, is a 27 kDa secreted activator protein that belongs to the R-Spondin family. R-Spondins positively regulate Wnt/beta-catenin signaling, most likely by acting as a ligand for LGR4-6 receptors and an inhibitor for ZNRF3. R-Spondin-1 induces proliferation of intestinal crypt epithelial cells, increases intestinal epithelial healing, and supports intestinal epithelial stem cell renewal [1-5]. The 293T cell line is stably transfected to express murine Rspo1 with an N-terminal HA epitope tag and fused to a C-terminal murine IgG2a Fc fragment. This cell line is used to produce either purified Rspo1 or Rspo1 conditioned media. The murine Rspo1 protein has been used extensively in organoid culture to maintain Lgr5+ stem cells, and the FC and HA tags make it easy to purify or characterize. |
Source | Trevigen |
TEMARICERCA
© 1995-2024 temaricerca.com - Tutti i diritti riservati - P.IVA 00674091202
Via XXI Ottobre 1944, 11/2, 40055 Castenaso (BO) - tel: 051 62 40 700 - fax: 051 62 40 706
© 1995-2024 temaricerca.com - Tutti i diritti riservati - P.IVA 00674091202
Via XXI Ottobre 1944, 11/2, 40055 Castenaso (BO) - tel: 051 62 40 700 - fax: 051 62 40 706