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Home > GENOMICS > EPIGENETIC PRODUCTS > Modulators & Inhibitors > Apicidin
Apicidin
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Code | SIH-346-5MG |
---|---|
Description | Apicidin |
Size | 5 mg |
General information | Cyclopeptide inhibitor of histone deactylases (HDACs). Inhibits HeLa cell proliferation (IC50=50- 100 nM) and induces reversible transcriptional activation of p21 (WAF1). Decreases HIF1α protein levels and transcriptional activity in human and mouse tumor cell lines. Cell permeable. |
ALTERNATIVE NAME | Cyclo(N-O-methyl-L-tryptophanyl-L Lisoleucinyl- Dpipecolinyl- L-2-amino-8-oxodecanoyl) |
Format | Lyophilized |
Application | HDAC inhibitor |
Class | Inhibitor |
Purity | >98% (HPLC); NMR (conforms) |
Storage | -20°C |
Data sheet | VIEW |
Research area | Epigenetics |
Source | StressMarq |
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© 1995-2024 temaricerca.com - Tutti i diritti riservati - P.IVA 00674091202
Via XXI Ottobre 1944, 11/2, 40055 Castenaso (BO) - tel: 051 62 40 700 - fax: 051 62 40 706