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PAI-1 ELISA KIT
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Code | EK0859 |
---|---|
Description | PAI-1 ELISA KIT |
Size | 1 x 96T |
General information | Plasminogen activator inhibitor-1 is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological breakdown of blood clots). It is a serine protease inhibitor (serpin) protein (SERPINE1). PAI-1 is mainly produced by the endothelium (cells lining blood vessels), but is also secreted by other tissue types, such as adipose tissue. The PAI-1 gene is located on the seventh chromosome (7q21.3-q22).1 Congenital deficiency of PAI-1 leads to a hemorrhagic diathesis (a tendency to hemorrhage). PAI-1 is present in increased levels in various disease states (such as a number of forms of cancer), as well as in obesity and the metabolic syndrome. It has been linked to the increased occurrence of thrombosis in patients with these conditions. Additionally, it has been shown to interact with ORM1.2 The standard product used in this kit is recombinant human PAI-1 with the molecular mass of 43KDa. |
Assay type | Complete kit |
Detection method | ELISA |
Sample type | Cell culture media, Serum, Plasma, Cell lysates |
Range detection | 156pg/ml-10,000pg/ml |
Sensitivity | < 10pg/ml |
Target species | Human |
Storage | S t o r e a t 4 ! f o r f r e q u e n t u s e , a t - 2 0 ! f o r i n f r e q u e n t u s e . A v o i d m u l t i p l e f r e e z e - t h a w c y c l e s |
Data sheet | VIEW |
Source | Boster Immunoleader |
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© 1995-2024 temaricerca.com - Tutti i diritti riservati - P.IVA 00674091202
Via XXI Ottobre 1944, 11/2, 40055 Castenaso (BO) - tel: 051 62 40 700 - fax: 051 62 40 706