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Home > PROTEOMICS > ELISA/CLIA/COLORIMETRIC KITS > Osteoactivin/GPNMB PicoKine ELISA KIT
Osteoactivin/GPNMB PicoKine ELISA KIT
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Code | EK1331 |
---|---|
Description | Osteoactivin/GPNMB PicoKine ELISA KIT |
Size | 1 x 96T |
General information | Transmembrane glycoprotein NMB is a protein that is encoded by the GPNMB gene. In osteoblast progenitor cells, GPNMB works as a positive regulator of osteoblast differentiation during later stages of matrix maturation and mineralization that is mediated at least in part by BMP-2 in a SMAD1 dependent manner to promote osteoblast differentiation. GPNMB can enhance the repairing process in bone fracture, demonstrated by its high expression during chondrogenesis(soft callus) and osteogenesis(hard callus) compared to the intact femurs that is why Osteoactivin(OA) could be a novel therapeutic agent used to treat generalized osteoporosis or localized osteopenia during fracture repair by stimulating bone growth and regeneration. Similarly, GPNMB expression increases during osteoclast differentiation and it is functionally implicated in this process, possibly by promoting the fusion of osteoclast progenitor cells. |
ALTERNATIVE NAME | Glycoprotein (transmembrane) nmb|Glycoprotein nmb|Glycoprotein nmb like protein|Gpnmb|GPNMB_HUMAN|HGFIN|NMB|Osteoactivin|Transmembrane glycoprotein|Transmembrane glycoprotein HGFIN|Transmembrane glycoprotein NMB |
Assay type | Complete kit |
Detection method | ELISA |
Sample type | Cell culture media, Serum, Plasma |
Range detection | 156pg/ml-10,000pg/ml |
Sensitivity | <10pg/ml |
Target species | Mouse |
Protein id | Q99P91 |
Storage | Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.) |
Data sheet | VIEW |
Research area | CYTOKINES AND GROWTH FACTORS |
Source | Boster Immunoleader |
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© 1995-2024 temaricerca.com - Tutti i diritti riservati - P.IVA 00674091202
Via XXI Ottobre 1944, 11/2, 40055 Castenaso (BO) - tel: 051 62 40 700 - fax: 051 62 40 706