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INCREASE EFFICIENCY OF GENOME EDITING USING THE Alt-R™ CRISPR-Cas9 SYSTEM

Alt-R™ CRISPR-Cas9 System

The Alt-R™ CRISPR-Cas9 System includes all of the reagents needed for successful genome editing. Based on the natural S. pyogenes CRISPR-Cas9 system, the Alt-R™CRISPR-Cas9 System offers numerous advantages over alternative methods:

 

  • Higher on-target potency than other CRISPR systems
  • Precise control of editing complex delivery with Cas9 ribonucleoprotein
  • Efficient delivery of the RNP with lipofection or electroporation
  • No toxicity or innate immune response activation as observed with in vitrotranscribed Cas9 mRNA and sgRNAs

 

 

   

                         

Benefits:

  • Focus on results with higher potency CRISPR reagents.
  • Save time and money with an efficient workflow and ready-to-use reagents.
  • Increase precision and reduce off-target editing using CRISPR-Cas9 ribonucleoprotein.
  • Adapt to your experimental needs with compatibility for lipofection or electroporation.

 

New! Alt-R™CRISPR crRNAs with increased nuclease resistance

 

IDT has updated the Alt-R™ CRISPR-Cas9 System with the addition of proprietary chemical modifications to the Alt-R™ CRISPR crRNA. These modifications protect the crRNA from degradation by cellular RNases, and further improve on-target editing performance. The modifications are included automatically to the final Alt-R™ CRISPR crRNA oligonucleotide sequence and do not require any changes to the ordering process.

 

PRODUCTS: