Epigenetics is the study of epigenetic inheritance, a set of reversible heritable changes in gene function or other cell phenotype that occur without a change in DNA sequence (genotype). These changes may be induced spontaneously, in response to environmental factors, or in response to the presence of a particular allele, even if it is absent from subsequent generations.
Many types of epigenetic processes have been identified--they include methylation, acetylation, phosphorylation, ubiquitylation, and sumolyation. Epigenetic processes are natural and essential to many organism functions, but if they occur improperly, there can be major adverse health and behavioral effects.
- Imprint Disorders.
- Immunity & Related Disorders.
- Neuropsychiatric Disorders.
- Pediatric Syndromes.
- David Rodenhiser and Mellissa Mann: CMAJ o 174: 2006
- Wikipedia: Epigenetics
- Bob Weinhold: Environmental Health Perspectives Volume 114: A160-A-167, 2006